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Compile Data Set for Download or QSAR

Found 2 hits of affinity data for UniProtKB/TrEMBL: Q9NQA5   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Transient receptor potential cation channel subfamily V member 5


(Homo sapiens)
BDBM50550078
PNG
(CHEMBL4777551)
Show SMILES O[C@]1(CC[C@@H](CC1)N1CCN(Cc2ccc(=O)[nH]c2)CC1)c1cccc(c1)C(F)(F)F |r,wU:4.7,1.23,(66.55,-8.01,;65.22,-8.79,;65.24,-7.25,;63.91,-6.46,;62.58,-7.22,;62.56,-8.77,;63.88,-9.55,;61.24,-6.45,;59.9,-7.21,;58.57,-6.43,;58.58,-4.88,;57.25,-4.1,;55.91,-4.87,;54.57,-4.09,;53.25,-4.87,;53.25,-6.42,;51.91,-7.19,;54.57,-7.18,;55.91,-6.42,;59.91,-4.11,;61.25,-4.9,;66.55,-9.57,;66.53,-11.1,;67.85,-11.88,;69.19,-11.13,;69.2,-9.58,;67.87,-8.81,;70.53,-8.82,;71.86,-9.6,;70.54,-7.29,;71.85,-8.04,)|
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PC cid
PC sid
PDB
UniChem
Article
PubMed
n/an/a 560n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of human TRPV5 expressed in HEK293 cells assessed as reduction in Cd2+ influx by calcium-5 fluorescence dye-based FLIPR assay


Citation and Details

Article DOI: 10.1039/d0md00145g
BindingDB Entry DOI: 10.7270/Q2FF3X0F
More data for this
Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 5


(Homo sapiens)
BDBM50511105
PNG
(GWP-42004 | Gwp42004 | O-4394 | THCV | Tetrahydroc...)
Show SMILES [H][C@@]12C=C(C)CC[C@@]1([H])C(C)(C)Oc1cc(CCC)cc(O)c21 |r,t:2|
Show InChI InChI=1S/C19H26O2/c1-5-6-13-10-16(20)18-14-9-12(2)7-8-15(14)19(3,4)21-17(18)11-13/h9-11,14-15,20H,5-8H2,1-4H3/t14-,15-/m1/s1
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PC cid
PC sid
PDB
UniChem
Article
PubMed
n/an/a 4.80E+3n/an/an/an/an/an/a


TBA



Citation and Details

Article DOI: 10.1021/acs.jnatprod.0c00965
BindingDB Entry DOI: 10.7270/Q2057KWP
More data for this
Ligand-Target Pair